HitPredict

Interactor 1: FGFR3 (P22607)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)
Gene: FGFR3

Interactor 2: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21487019
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 806 Hs			1 840
+	Hs
		320811 FGFR3_HUMAN (10-806): 0: 819: 100.00		HS74L_HUMAN (1-840): 0: 959: 63.21
+	Hs
		1072565 EPHA7_HUMAN (1-782): 0: 626: 21.22		HS105_HUMAN (1-840): 0: 938: 62.95
+	Hs
		320817 EPHA8_HUMAN (1-771): 0: 593: 20.56		HS74L_HUMAN (1-840): 0: 959: 63.21
+	Hs
		665505 EPHA8_HUMAN (1-771): 0: 593: 20.56		HS105_HUMAN (1-840): 0: 938: 62.95
+	Hs
		320862 NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59		HS74L_HUMAN (1-840): 0: 959: 63.21
+	Hs
		1081553 NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59		HS105_HUMAN (1-840): 0: 938: 62.95
+	Hs
		384373 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Hs
		320790 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		HS74L_HUMAN (1-840): 0: 959: 63.21
+	Hs
		385266 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		HS105_HUMAN (1-840): 0: 938: 62.95
+	Hs
		320822 VGFR3_HUMAN (7-245): 8.53e-15: 81: 18.22		HS74L_HUMAN (1-840): 0: 959: 63.21
+	Hs
		320803 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		HS74L_HUMAN (1-840): 0: 959: 63.21
+	Hs
		729325 VGFR3_HUMAN (7-245): 8.53e-15: 81: 18.22		HS105_HUMAN (1-840): 0: 938: 62.95
+	Hs
		503438 FGFR3_HUMAN (10-806): 0: 819: 100.00		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		503499 EPHB2_HUMAN (1-788): 0: 624: 19.15		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		384163 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		384372 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48
+	Hs
		384219 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86
+	Hs
		507880 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48
+	Hs
		507836 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86