HitPredict

Interactor 1: FGFR3 (P22607)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)
Gene: FGFR3

Interactor 2: RADI (P35241)
Radixin
Gene: RDX

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~PK_Tyr_Ser-Thr
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 806 Hs			1 583
+	Hs
		505551 FGFR3_HUMAN (10-806): 0: 819: 100.00		EPB41_HUMAN (3-553): 1.19e-125: 392: 20.48
+	Hs
		299238 FGFR3_HUMAN (10-806): 0: 819: 100.00		FARP2_HUMAN (2-582): 1.86e-110: 356: 18.76
+	Hs
		665555 EPHB2_HUMAN (1-788): 0: 624: 19.15		RADI_HUMAN (1-583): 3.49e-166: 487: 100.00
+	Hs
		719689 EPHA5_HUMAN (1-777): 0: 622: 20.18		RADI_HUMAN (1-583): 3.49e-166: 487: 100.00
+	Hs
		640048 EPHB2_HUMAN (1-788): 0: 624: 19.15		MOES_HUMAN (1-583): 2.8e-161: 474: 80.96
+	Hs
		546943 EPHA2_HUMAN (1-788): 0: 595: 21.50		EZRI_HUMAN (1-583): 3.17e-166: 487: 76.28
+	Hs
		665554 EPHB2_HUMAN (1-788): 0: 624: 19.15		MERL_HUMAN (2-583): 1.72e-151: 450: 45.30
+	Hs
		665158 EPHA2_HUMAN (1-788): 0: 595: 21.50		MERL_HUMAN (2-583): 1.72e-151: 450: 45.30
+	Hs
		719722 NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59		RADI_HUMAN (1-583): 3.49e-166: 487: 100.00
+	Hs
		719502 NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59		MERL_HUMAN (2-583): 1.72e-151: 450: 45.30
+	Hs
		384207 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		EZRI_HUMAN (1-583): 3.17e-166: 487: 76.28
+	Hs
		384378 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		RADI_HUMAN (1-583): 3.49e-166: 487: 100.00
+	Hs
		1083898 NTRK2_HUMAN (159-756): 1.53e-161: 491: 25.51		E41L5_HUMAN (5-567): 7.64e-125: 385: 19.55
+	Mm
		546328 NTRK2_MOUSE (158-756): 2.71e-161: 490: 25.19		E41L3_MOUSE (2-547): 1.36e-119: 377: 21.15
+	Hs
		384164 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		EPB41_HUMAN (3-553): 1.19e-125: 392: 20.48
+	Hs
		385554 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		E41L5_HUMAN (5-567): 7.64e-125: 385: 19.55
+	Hs
		434145 RET_HUMAN (453-801): 9.71e-98: 330: 48.63		RADI_HUMAN (1-583): 3.49e-166: 487: 100.00
+	Hs
		434144 RET_HUMAN (453-801): 9.71e-98: 330: 48.63		MERL_HUMAN (2-583): 1.72e-151: 450: 45.30
+	Hs
		546957 TIE1_HUMAN (464-782): 5.85e-69: 249: 44.51		EZRI_HUMAN (1-583): 3.17e-166: 487: 76.28
+	Mm
		1206834 PTK7_MOUSE (160-362): 3.3e-16: 85.6: 17.96		E41L3_MOUSE (2-547): 1.36e-119: 377: 21.15