HitPredict

Interactor 1: FGFR3 (P22607)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)
Gene: FGFR3

Interactor 2: GABP1 (Q06547)
GA-binding protein subunit beta-1 (GABP subunit beta-1) (GABPB-1) (GABP subunit beta-2) (GABPB-2) (Nuclear respiratory factor 2) (Transcription factor E4TF1-47) (Transcription factor E4TF1-53)
Gene: GABPB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.594

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~I-set
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 806 Hs			1 395
+	Hs
		665581 EPHB2_HUMAN (1-788): 0: 624: 19.15		ANK2_HUMAN (78-390): 1.79e-61: 216: 14.78
+	Hs
		665439 EPHA3_HUMAN (1-786): 0: 641: 20.68		KDIS_HUMAN (1-189): 1.48e-43: 164: 25.79
+	Hs
		872504 EPHA5_HUMAN (1-777): 0: 622: 20.18		KDIS_HUMAN (1-189): 1.48e-43: 164: 25.79
+	Hs
		665360 EPHA2_HUMAN (1-788): 0: 595: 21.50		KDIS_HUMAN (1-189): 1.48e-43: 164: 25.79
+	Hs
		665591 EPHB2_HUMAN (1-788): 0: 624: 19.15		ANK3_HUMAN (288-395): 2.96e-10: 64.6: 7.27
+	Hs
		1081644 NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59		KDIS_HUMAN (1-189): 1.48e-43: 164: 25.79
+	Hs
		384666 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		ANK2_HUMAN (78-390): 1.79e-61: 216: 14.78
+	Hs
		1083907 NTRK2_HUMAN (159-756): 1.53e-161: 491: 25.51		KDIS_HUMAN (1-189): 1.48e-43: 164: 25.79
+	Rn
		728451 NTRK1_RAT (158-757): 1.01e-158: 483: 26.09		KDIS_RAT (1-189): 1.49e-43: 164: 25.26
+	Hs
		385704 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		KDIS_HUMAN (1-189): 1.48e-43: 164: 25.79
+	Hs
		166874 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		ANR28_HUMAN (144-395): 4.7e-34: 136: 14.23
+	Hs
		1021409 NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59		ANK3_HUMAN (288-395): 2.96e-10: 64.6: 7.27
+	Hs
		385170 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		ANR44_HUMAN (2-136): 4.91e-28: 118: 27.86
+	Hs
		385487 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		TANC1_HUMAN (10-151): 4.4e-15: 79.3: 34.97
+	Hs
		257545 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		ANR17_HUMAN (1-60): 1.55e-10: 65.3: 26.23
+	Hs
		434183 RET_HUMAN (453-801): 9.71e-98: 330: 48.63		ANK3_HUMAN (288-395): 2.96e-10: 64.6: 7.27
+	Hs
		507954 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		ANK2_HUMAN (78-390): 1.79e-61: 216: 14.78
+	Hs
		507831 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		ANK1_HUMAN (168-392): 1.69e-27: 116: 7.97
+	Hs
		508185 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		TANC1_HUMAN (10-151): 4.4e-15: 79.3: 34.97
+	Hs
		507971 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		ANK3_HUMAN (288-395): 2.96e-10: 64.6: 7.27