HitPredict

Interactor 1: FGFR3 (P22607)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)
Gene: FGFR3

Interactor 2: FHL3 (Q13643)
Four and a half LIM domains protein 3 (FHL-3) (Skeletal muscle LIM-protein 2) (SLIM-2)
Gene: FHL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	33961781, 35384245
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 806 Hs			1 280
+	Hs
		609352 FGFR3_HUMAN (10-806): 0: 819: 100.00		ABLM2_HUMAN (3-148): 1.19e-24: 104: 22.93
+	Hs
		738207 FLT3_HUMAN (11-791): 1.67e-162: 499: 23.74		FHL3_HUMAN (1-280): 8.02e-79: 241: 100.00
+	Hs
		150580 NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59		ABLM1_HUMAN (3-147): 6.59e-28: 114: 24.03
+	Hs
		385342 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		PDLI5_HUMAN (3-155): 6.13e-48: 169: 28.76
+	Hs
		150581 NTRK2_HUMAN (159-756): 1.53e-161: 491: 25.51		ABLM1_HUMAN (3-147): 6.59e-28: 114: 24.03
+	Hs
		434295 RET_HUMAN (453-801): 9.71e-98: 330: 48.63		PDLI7_HUMAN (158-278): 1.55e-32: 126: 24.79
+	Hs
		729275 VGFR3_HUMAN (7-245): 8.53e-15: 81: 18.22		FHL3_HUMAN (1-280): 8.02e-79: 241: 100.00
+	Hs
		572633 VGFR1_HUMAN (40-357): 6.77e-13: 74.8: 13.25		FHL3_HUMAN (1-280): 8.02e-79: 241: 100.00
+	Hs
		607962 FGFR4_HUMAN (1-130): 1.18e-11: 70.5: 19.31		FHL3_HUMAN (1-280): 8.02e-79: 241: 100.00
+	Hs
		508136 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		LPP_HUMAN (3-153): 3.55e-38: 143: 29.38
+	Hs
		150510 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		ABLM1_HUMAN (3-147): 6.59e-28: 114: 24.03
+	Hs
		150520 FGFR4_HUMAN (1-130): 1.18e-11: 70.5: 19.31		ABLM1_HUMAN (3-147): 6.59e-28: 114: 24.03