HitPredict

Interactor 1: FGFR3 (P22607)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)
Gene: FGFR3

Interactor 2: DYN3 (Q9UQ16)
Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin)
Gene: DNM3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 806 Hs			1 869
+	Hs
		609215 FGFR3_HUMAN (10-806): 0: 819: 100.00		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		384503 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		384691 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		DYN1_HUMAN (1-852): 0: 1035: 78.56
+	Hs
		128396 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		DNM1L_HUMAN (6-750): 0: 788: 38.25
+	Hs
		508270 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		DYN3_HUMAN (1-869): 0: 1080: 100.00
+	Hs
		601616 FGFR2_HUMAN (1-114): 9.04e-12: 70.9: 17.56		DYN3_HUMAN (1-869): 0: 1080: 100.00
+	Hs
		608198 FGFR4_HUMAN (1-130): 1.18e-11: 70.5: 19.31		DYN3_HUMAN (1-869): 0: 1080: 100.00
+	Hs
		729628 VGFR2_HUMAN (5-342): 3.81e-17: 88.6: 16.58		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		507913 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		572603 VGFR1_HUMAN (40-357): 6.77e-13: 74.8: 13.25		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		601480 FGFR2_HUMAN (1-114): 9.04e-12: 70.9: 17.56		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		607921 FGFR4_HUMAN (1-130): 1.18e-11: 70.5: 19.31		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		231041 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		OPA1_HUMAN (7-660): 1.13e-158: 490: 19.02