HitPredict

Interactor 1: A5PJS1 (A5PJS1)
Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5)
Gene: GNB5

Interactor 2: RGS9 (O46469)
Regulator of G-protein signaling 9 (RGS9)
Gene: RGS9

Species: Bos taurus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	10051575
Identification Methods	coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DEP~WD40, G-gamma~WD40, RGS~WD40, RGS_DHEX~WD40
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 353 Bt			1 484
+	Hs
		154648 GNB5_HUMAN (1-353): 2.35e-102: 308: 99.15		RGS9_HUMAN (1-483): 0: 652: 89.10
+	Mm
		222406 GNB5_MOUSE (1-353): 1.2e-102: 309: 99.15		RGS9_MOUSE (1-483): 0: 646: 89.44
+	Hs
		154649 GNB5_HUMAN (1-353): 2.35e-102: 308: 99.15		RGS11_HUMAN (13-465): 0: 605: 52.31
+	Hs
		154665 GNB5_HUMAN (1-353): 2.35e-102: 308: 99.15		RGS7_HUMAN (9-449): 0: 584: 35.89
+	Hs
		154664 GNB5_HUMAN (1-353): 2.35e-102: 308: 99.15		RGS6_HUMAN (8-424): 0: 572: 37.50
+	Hs
		833687 GBB4_HUMAN (2-181): 3.18e-30: 119: 13.12		RGS6_HUMAN (8-424): 0: 572: 37.50
+	Hs
		833678 GBB1_HUMAN (2-133): 1.38e-16: 81.7: 12.59		RGS6_HUMAN (8-424): 0: 572: 37.50
+	Hs
		560862 GBB3_HUMAN (2-133): 5.17e-16: 79.7: 11.11		RGS6_HUMAN (8-424): 0: 572: 37.50
+	Hs
		833679 GBB2_HUMAN (278-353): 5.25e-11: 65.1: 17.11		RGS6_HUMAN (8-424): 0: 572: 37.50
+	Ce
		184655 GBB2_CAEEL (2-180): 1.9e-33: 129: 11.60		O17589_CAEEL (14-478): 8.52e-159: 460: 30.67
+	Ce
		184654 GBB1_CAEEL (278-353): 2.13e-10: 63.2: 17.11		O17589_CAEEL (14-478): 8.52e-159: 460: 30.67
+	Ce
		834951 GBB2_CAEEL (2-180): 1.9e-33: 129: 11.60		EGL10_CAEEL (209-423): 8.43e-67: 226: 32.89
+	Ce
		567430 GBB1_CAEEL (278-353): 2.13e-10: 63.2: 17.11		EGL10_CAEEL (209-423): 8.43e-67: 226: 32.89