HitPredict

Interactor 1: CCNO (P22674)
Cyclin-O
Gene: CCNO

Interactor 2: CKS1 (P61024)
Cyclin-dependent kinases regulatory subunit 1 (CKS-1)
Gene: CKS1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0044772 - mitotic cell cycle phase transition GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 350 Hs			1 79
+	Hs
		303840 CCNB2_HUMAN (14-345): 1.8e-102: 308: 21.37		CKS1_HUMAN (1-79): 9.36e-40: 127: 100.00
+	At
		188149 CCB12_ARATH (5-345): 3.06e-102: 310: 24.86		CKS1_ARATH (5-73): 1.35e-37: 122: 69.57
+	Hs
		538505 CCNB1_HUMAN (2-346): 1.61e-100: 305: 19.39		CKS1_HUMAN (1-79): 9.36e-40: 127: 100.00
+	At
		1106919 CCB12_ARATH (5-345): 3.06e-102: 310: 24.86		CKS2_ARATH (5-78): 3.45e-37: 120: 67.57
+	Hs
		303832 CCNB2_HUMAN (14-345): 1.8e-102: 308: 21.37		CKS2_HUMAN (1-79): 5.68e-38: 122: 81.01
+	Hs
		538483 CCNB1_HUMAN (2-346): 1.61e-100: 305: 19.39		CKS2_HUMAN (1-79): 5.68e-38: 122: 81.01
+	Hs
		895411 CCNA1_HUMAN (73-345): 7.93e-97: 296: 25.36		CKS1_HUMAN (1-79): 9.36e-40: 127: 100.00
+	Hs
		590156 CCNA2_HUMAN (2-345): 1.71e-96: 294: 23.92		CKS1_HUMAN (1-79): 9.36e-40: 127: 100.00
+	At
		188148 CCA23_ARATH (20-345): 7.15e-97: 296: 21.28		CKS1_ARATH (5-73): 1.35e-37: 122: 69.57
+	At
		188178 CCB24_ARATH (2-341): 2.32e-97: 296: 22.22		CKS1_ARATH (5-73): 1.35e-37: 122: 69.57
+	Hs
		706795 CCNA1_HUMAN (73-345): 7.93e-97: 296: 25.36		CKS2_HUMAN (1-79): 5.68e-38: 122: 81.01
+	At
		1352139 CCB24_ARATH (2-341): 2.32e-97: 296: 22.22		CKS2_ARATH (5-78): 3.45e-37: 120: 67.57
+	Hs
		590135 CCNA2_HUMAN (2-345): 1.71e-96: 294: 23.92		CKS2_HUMAN (1-79): 5.68e-38: 122: 81.01
+	Hs
		610198 CCNO_HUMAN (1-350): 2.69e-97: 293: 100.00		CKS2_HUMAN (1-79): 5.68e-38: 122: 81.01
+	At
		188134 CCB14_ARATH (13-345): 3.05e-95: 290: 22.97		CKS1_ARATH (5-73): 1.35e-37: 122: 69.57
+	At
		1324477 CCA31_ARATH (14-346): 3.44e-96: 291: 22.92		CKS2_ARATH (5-78): 3.45e-37: 120: 67.57
+	At
		188167 CCB23_ARATH (2-341): 3.25e-93: 286: 22.79		CKS1_ARATH (5-73): 1.35e-37: 122: 69.57
+	At
		188151 CCA34_ARATH (7-346): 2.89e-91: 279: 22.25		CKS1_ARATH (5-73): 1.35e-37: 122: 69.57
+	At
		1108315 CCA34_ARATH (7-346): 2.89e-91: 279: 22.25		CKS2_ARATH (5-78): 3.45e-37: 120: 67.57
+	At
		48925 CCA33_ARATH (39-346): 2.37e-90: 275: 22.68		CKS1_ARATH (5-73): 1.35e-37: 122: 69.57