HitPredict

Interactor 1: CBL (P22682)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Interactor 2: IRF8 (P23611)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (ICSBP)
Gene: IRF8

Species: Mus musculus

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	21731497
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 913 Mm			1 424
+	Hs
		610358 CBL_HUMAN (1-913): 0: 894: 91.05		IRF8_HUMAN (1-424): 0: 574: 89.67
+	Hs
		610411 CBL_HUMAN (1-913): 0: 894: 91.05		IRF4_HUMAN (6-384): 4.64e-155: 447: 42.27
+	Hs
		610404 CBL_HUMAN (1-913): 0: 894: 91.05		IRF3_HUMAN (9-388): 6.95e-146: 423: 28.72
+	Hs
		500995 CBL_HUMAN (1-913): 0: 894: 91.05		IRF1_HUMAN (9-266): 9.31e-86: 266: 27.27
+	Hs
		1071055 KMT2C_HUMAN (425-900): 5.82e-11: 69.2: 12.40		IRF4_HUMAN (6-384): 4.64e-155: 447: 42.27
+	Hs
		257600 ANR17_HUMAN (449-911): 1.89e-09: 64.2: 8.33		IRF9_HUMAN (5-385): 1.13e-130: 383: 34.01