HitPredict

Interactor 1: CBL (P22682)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Interactor 2: HMGB2 (P30681)
High mobility group protein B2 (High mobility group protein 2) (HMG-2)
Gene: HMGB2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	27474268
Identification Methods	affinity chromatography technology
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008584 - male gonad development GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 913 Mm			1 210
+	Hs
		643341 CBLB_HUMAN (23-908): 0: 799: 45.92		HMGB2_HUMAN (1-187): 9.56e-42: 142: 98.40
+	Hs
		449694 ZO1_HUMAN (435-850): 6.77e-22: 104: 14.39		HMGB1_HUMAN (1-174): 1.07e-43: 147: 85.63
+	Hs
		818266 KMT2C_HUMAN (425-900): 5.82e-11: 69.2: 12.40		SOX2_HUMAN (3-94): 9.85e-25: 100: 22.83
+	Hs
		1243837 KMT2C_HUMAN (425-900): 5.82e-11: 69.2: 12.40		SOX7_HUMAN (3-90): 1.34e-23: 98.6: 23.86
+	Hs
		1243843 KMT2C_HUMAN (425-900): 5.82e-11: 69.2: 12.40		SOX17_HUMAN (6-90): 1.48e-23: 98.6: 22.35
+	Hs
		257583 ANR17_HUMAN (449-911): 1.89e-09: 64.2: 8.33		SOX2_HUMAN (3-94): 9.85e-25: 100: 22.83
+	Hs
		1295393 CHAP1_HUMAN (427-827): 1.87e-11: 70: 12.53		CIC_HUMAN (3-100): 5.25e-11: 63.2: 22.45