HitPredict

Interactor 1: CBL (P22682)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Interactor 2: 1433E (P62259)
14-3-3 protein epsilon (14-3-3E)
Gene: Ywhae

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	16944949, 27474268
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0030424 - axon
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 913 Mm			1 255
+	Hs
		610330 CBL_HUMAN (1-913): 0: 894: 91.05		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		297821 K0754_HUMAN (544-913): 1.34e-28: 126: 15.54		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909489 ARHG5_HUMAN (429-854): 3.49e-10: 66.4: 15.87		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		257595 ANR17_HUMAN (449-911): 1.89e-09: 64.2: 8.33		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909712 OTOG_HUMAN (408-700): 1.58e-09: 64.2: 13.85		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00