HitPredict

Interactor 1: CBL (P22682)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Interactor 2: TBB4B (P68372)
Tubulin beta-4B chain (Tubulin beta-2C chain)
Gene: Tubb4b

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	27474268
Identification Methods	affinity chromatography technology
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 913 Mm			1 445
+	Mm
		610583 CBL_MOUSE (1-913): 0: 923: 100.00		TBB5_MOUSE (1-429): 0: 711: 98.37
+	Hs
		610390 CBL_HUMAN (1-913): 0: 894: 91.05		TBB3_HUMAN (1-443): 0: 714: 93.23
+	Hs
		428020 CBL_HUMAN (1-913): 0: 894: 91.05		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		610348 CBL_HUMAN (1-913): 0: 894: 91.05		TBB4B_HUMAN (1-427): 0: 711: 100.00
+	Hs
		610500 CBL_HUMAN (1-913): 0: 894: 91.05		TBB2B_HUMAN (1-430): 0: 710: 98.14
+	Hs
		610394 CBL_HUMAN (1-913): 0: 894: 91.05		TBB2A_HUMAN (1-430): 0: 707: 97.67
+	Hs
		990836 ZO1_HUMAN (435-850): 6.77e-22: 104: 14.39		TBB3_HUMAN (1-443): 0: 714: 93.23
+	Hs
		428157 ZO1_HUMAN (435-850): 6.77e-22: 104: 14.39		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		381173 ZO1_HUMAN (435-850): 6.77e-22: 104: 14.39		TBB4A_HUMAN (1-427): 0: 706: 98.60