Interactor 1: KAPCB (P22694)
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)
Gene: PRKACB

Interactor 2: ACV1B (P36896)
Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)
Gene: ACVR1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 21988832
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase, Pkinase~TGF_beta_GS
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 351
Hs

1 505
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024