HitPredict

Interactor 1: KAPCB (P22694)
cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11)
Gene: PRKACB

Interactor 2: GP161 (Q8N6U8)
G-protein coupled receptor 161 (G-protein coupled receptor RE2)
Gene: GPR161

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	33961781, 28514442, 32707033
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	7tm_1~Pkinase
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 351 Hs			1 529
+	Hs
		568733 KAPCA_HUMAN (1-351): 3.72e-164: 463: 92.88		GP161_HUMAN (1-529): 5.45e-144: 426: 100.00
+	Hs
		609681 KAPCG_HUMAN (1-351): 5.62e-161: 456: 78.63		GP161_HUMAN (1-529): 5.45e-144: 426: 100.00
+	Hs
		568537 KAPCA_HUMAN (1-351): 3.72e-164: 463: 92.88		DRD1_HUMAN (9-379): 6.57e-74: 243: 19.38
+	Mm
		397200 KAPCA_MOUSE (1-351): 1.06e-162: 460: 92.02		ADRB1_MOUSE (44-360): 3.59e-74: 244: 21.88