HitPredict

Interactor 1: GRIK1 (P22756)
Glutamate receptor ionotropic, kainate 1 (GluK1) (Glutamate receptor 5) (GluR-5) (GluR5)
Gene: GRIK1

Interactor 2: GRIK2 (P42260)
Glutamate receptor ionotropic, kainate 2 (GluK2) (Glutamate receptor 6) (GluR-6) (GluR6)
Gene: GRIK2

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 34706237
Identification Methods pull down
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANF_receptor, ANF_receptor~Lig_chan, ANF_receptor~Lig_chan-Glu_bd, Lig_chan~Lig_chan, Lig_chan~Lig_chan-Glu_bd, Lig_chan-Glu_bd~Lig_chan-Glu_bd
Common GO terms GO:0000149 - SNARE binding
GO:0004970 - glutamate-gated receptor activity
GO:0005234 - extracellularly glutamate-gated ion channel activity
GO:0005886 - plasma membrane
GO:0007268 - chemical synaptic transmission
and 24 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 949
Rn

1 908
+ Hs
+ Hs
+ Rn
+ Rn
+ Rn
+ Hs
+ Hs
+ Mm
+ Rn
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024