HitPredict

Interactor 1: TRX2 (P22803)
Thioredoxin-2 (Thioredoxin II) (TR-II) (Thioredoxin-1)
Gene: TRX2

Interactor 2: TSA2 (Q04120)
Peroxiredoxin TSA2 (Prx) (EC 1.11.1.24) (Cytoplasmic thiol peroxidase 2) (cTPx 2) (Thiol-specific antioxidant protein 2) (Thioredoxin peroxidase type Ib) (TPx type Ib) (Thioredoxin-dependent peroxiredoxin TSA2)
Gene: TSA2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	23414292, 27816612
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	1-cysPrx_C~Thioredoxin, AhpC-TSA~Thioredoxin
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045454 - cell redox homeostasis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 104 Sc			1 196
+	Hs
		495475 THIO_HUMAN (1-104): 2.21e-36: 120: 48.57		PRDX2_HUMAN (4-195): 6.97e-103: 296: 61.98
+	Mm
		956730 THIOM_MOUSE (5-104): 3.85e-34: 117: 31.37		PRDX2_MOUSE (4-195): 1.06e-102: 295: 61.98
+	Hs
		495510 THIO_HUMAN (1-104): 2.21e-36: 120: 48.57		PRDX1_HUMAN (4-193): 2.58e-98: 284: 58.64
+	Mm
		589514 THIOM_MOUSE (5-104): 3.85e-34: 117: 31.37		PRDX3_MOUSE (3-195): 1.28e-98: 287: 57.00
+	Mm
		139927 THIOM_MOUSE (5-104): 3.85e-34: 117: 31.37		PRDX4_MOUSE (4-195): 9.51e-97: 283: 52.60
+	Mm
		727682 THIOM_MOUSE (5-104): 3.85e-34: 117: 31.37		PRDX1_MOUSE (4-193): 8.61e-98: 283: 58.64
+	Hs
		531737 PDIA4_HUMAN (3-103): 9.76e-27: 104: 21.30		PRDX3_HUMAN (2-195): 6.63e-101: 293: 56.70
+	Hs
		685729 TXND5_HUMAN (23-104): 8.07e-26: 100: 26.14		PRDX2_HUMAN (4-195): 6.97e-103: 296: 61.98
+	Sc
		611720 TRX2_YEAST (1-104): 5.03e-39: 127: 100.00		TSA1_YEAST (1-195): 1.7e-91: 267: 86.15
+	Hs
		1026686 PDIA6_HUMAN (6-98): 2.01e-29: 110: 22.92		PRDX4_HUMAN (4-195): 4.02e-96: 281: 53.13
+	Sc
		606199 TRX1_YEAST (1-103): 9.82e-38: 124: 78.64		TSA1_YEAST (1-195): 1.7e-91: 267: 86.15
+	Hs
		531815 PDIA4_HUMAN (3-103): 9.76e-27: 104: 21.30		PRDX4_HUMAN (4-195): 4.02e-96: 281: 53.13
+	Sc
		606220 TRX1_YEAST (1-103): 9.82e-38: 124: 78.64		TSA2_YEAST (1-196): 1.09e-88: 260: 100.00
+	Hs
		1026726 TXND5_HUMAN (23-104): 8.07e-26: 100: 26.14		PRDX4_HUMAN (4-195): 4.02e-96: 281: 53.13
+	So
		188731 TRXM_SPIOL (2-104): 2.48e-35: 120: 33.65		BAS1_SPIOL (3-194): 1.05e-87: 260: 49.22
+	Ss
		852832 THIO_SYNY3 (6-104): 1.03e-34: 116: 33.66		Y755_SYNY3 (3-194): 1.98e-89: 262: 44.56
+	At
		1280846 TRXF1_ARATH (2-101): 4.65e-33: 114: 35.64		BAS1A_ARATH (3-194): 1.06e-87: 260: 48.97
+	Ss
		852787 THIO_SYNY3 (6-104): 1.03e-34: 116: 33.66		P73348_SYNY3 (1-192): 3.6e-70: 214: 26.02
+	Sc
		630634 TRX3_YEAST (2-103): 7.69e-35: 117: 42.16		PRX1_YEAST (3-195): 9.66e-69: 212: 27.32
+	Dm
		1177773 THIO2_DROME (1-104): 6.96e-33: 111: 43.40		Q7JX87_DROME (3-190): 3.03e-69: 211: 28.64