HitPredict

Interactor 1: SLOU (P22807)
Homeobox protein slou (Homeobox protein NK-1) (Protein slouch) (S59/2)
Gene: SLOU

Interactor 2: UBX (P83949)
Homeotic protein ultrabithorax
Gene: UBX

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	25869471, 30247122
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Homeodomain~Homeodomain
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 659 Dm			1 389
+	Dm
		611798 SLOU_DROME (1-659): 1.84e-165: 491: 100.00		ABDA_DROME (260-376): 4.98e-42: 157: 59.32
+	Dm
		367176 SLOU_DROME (1-659): 1.84e-165: 491: 100.00		ANTP_DROME (161-375): 5.32e-31: 123: 32.56
+	Dm
		447319 SLOU_DROME (1-659): 1.84e-165: 491: 100.00		SCR_DROME (289-353): 5.65e-24: 104: 80.00
+	Dm
		950052 Q9VDF0_DROME (407-618): 1.31e-32: 130: 25.46		UBX_DROME (1-389): 3.26e-124: 365: 100.00
+	Dm
		950100 Q9W1H7_DROME (480-646): 1.08e-33: 130: 24.55		UBX_DROME (1-389): 3.26e-124: 365: 100.00
+	Hs
		620134 PAX7_HUMAN (521-653): 5.23e-32: 132: 31.34		MNX1_HUMAN (197-387): 6.03e-52: 179: 33.67
+	Dm
		668281 Q9VDF0_DROME (407-618): 1.31e-32: 130: 25.46		ABDA_DROME (260-376): 4.98e-42: 157: 59.32
+	Dm
		668312 Q9W1H7_DROME (480-646): 1.08e-33: 130: 24.55		ABDA_DROME (260-376): 4.98e-42: 157: 59.32
+	Hs
		446885 HXC4_HUMAN (534-641): 1.7e-34: 133: 37.04		HXB5_HUMAN (193-367): 3.02e-37: 137: 36.00
+	Hs
		453052 HXA7_HUMAN (418-615): 3.24e-37: 140: 22.61		HXB7_HUMAN (139-364): 7.88e-33: 124: 31.86
+	Hs
		678782 ALX4_HUMAN (344-658): 2.86e-31: 128: 17.07		HXD3_HUMAN (213-387): 2.01e-35: 136: 33.14
+	Mm
		620871 Q5U4D4_MOUSE (235-612): 4.84e-34: 139: 14.59		HXD12_MOUSE (132-359): 2.35e-32: 124: 26.67
+	Hs
		453048 HXB7_HUMAN (427-616): 5.29e-36: 136: 22.17		HXA5_HUMAN (120-367): 8.65e-32: 123: 31.73
+	Hs
		174008 SHOX_HUMAN (476-607): 3.2e-32: 128: 28.79		SHOX_HUMAN (234-376): 1.27e-33: 128: 21.62
+	Hs
		211800 MSX2_HUMAN (541-655): 1.73e-33: 131: 38.46		TLX3_HUMAN (118-388): 1.09e-31: 123: 17.34
+	Hs
		980974 ALX4_HUMAN (344-658): 2.86e-31: 128: 17.07		EMX1_HUMAN (110-370): 5.74e-32: 124: 17.42
+	Mm
		623693 PAX3_MOUSE (471-655): 6.3e-31: 128: 22.73		MEOX1_MOUSE (149-378): 2.72e-32: 123: 18.93
+	Mm
		623694 PAX3_MOUSE (471-655): 6.3e-31: 128: 22.73		MEOX2_MOUSE (114-366): 8.16e-32: 123: 19.76
+	Hs
		568043 ALX4_HUMAN (344-658): 2.86e-31: 128: 17.07		HXB6_HUMAN (161-372): 7.83e-31: 119: 31.13