Interactor 1: CNOT1 (A5YKK6)
CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1) (Negative regulator of transcription subunit 1 homolog) (NOT1H) (hNOT1)
Gene: CNOT1

Interactor 2: CNOT1 (A5YKK6)
CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1) (Negative regulator of transcription subunit 1 homolog) (NOT1H) (hNOT1)
Gene: CNOT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 22977175
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CNOT1_CAF1_bind~CNOT1_CAF1_bind, CNOT1_HEAT~CNOT1_HEAT, CNOT1_HEAT~CNOT1_TTP_bind, Not1~Not1
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 - P-body
GO:0001829 - trophectodermal cell differentiation
and 22 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 2376
Hs

1 2376
+ Sc

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Last updated: 15 Jul 2024