HitPredict

Interactor 1: EIF3A (P23116)
Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Centrosomin) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (p162)
Gene: EIF3A

Interactor 2: EED (Q921E6)
Polycomb protein EED
Gene: EED

Species: Mus musculus

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1344 Mm			1 441
+	Hs
		268083 EIF3A_HUMAN (1-1344): 2.21e-125: 424: 88.87		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		903218 EIF3A_HUMAN (1-1344): 2.21e-125: 424: 88.87		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		267923 MYH10_HUMAN (306-1298): 1.37e-41: 170: 10.16		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		93875 E9QPE7_MOUSE (186-1097): 1.03e-32: 141: 9.53		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Mm
		70592 B2RR82_MOUSE (528-912): 1.13e-28: 127: 17.54		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		267922 MYH9_HUMAN (842-1344): 2.55e-16: 87.2: 8.27		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		1265608 PLEC_MOUSE (500-1336): 3.1e-15: 83.9: 14.29		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		268143 NIPBL_HUMAN (600-1301): 2.09e-14: 81: 15.82		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		1186814 MRCKB_MOUSE (369-922): 5.9e-14: 79.5: 17.68		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		268102 PLEC_HUMAN (500-1336): 1e-13: 78.9: 13.82		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		1265600 MY18A_MOUSE (410-909): 1.41e-11: 71.6: 10.28		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Mm
		1257473 MYH9_MOUSE (938-1344): 4.51e-11: 69.9: 5.90		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Sc
		747018 EIF3A_YEAST (7-933): 1.91e-59: 224: 22.36		COPA_YEAST (15-182): 2.3e-11: 68.1: 10.71
+	Hs
		725215 MYH10_HUMAN (306-1298): 1.37e-41: 170: 10.16		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		1281519 MRCKB_HUMAN (522-1016): 2.97e-17: 90.1: 12.72		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		724952 MYH9_HUMAN (842-1344): 2.55e-16: 87.2: 8.27		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		1068625 PLEC_HUMAN (500-1336): 1e-13: 78.9: 13.82		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		903375 BD1L1_HUMAN (470-1324): 1.77e-24: 114: 12.41		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		61736 A6H8W8_HUMAN (745-1128): 2.6e-11: 70.8: 12.94		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		903240 PLEC_HUMAN (500-1336): 1e-13: 78.9: 13.82		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09