Interactor 1: TCEA1 (P23193)
Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1) (Transcription elongation factor TFIIS.o)
Gene: TCEA1
Interactor 2: RPB1 (P24928)
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)
Gene: POLR2A
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.965 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9765293, 9305922, 17643375, 20178742, 12914699, 16916636, 23748380, 20562857 |
| Identification Methods | pull down, affinity chromatography technology, x-ray crystallography, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | RNA_pol_Rpb1_2~TFIIS_C, RNA_pol_Rpb1_3~TFIIS_C, RNA_pol_Rpb1_4~TFIIS_C, RNA_pol_Rpb1_5~TFIIS_C, RNA_pol_Rpb1_4~TFIIS_M, RNA_pol_Rpb1_5~TFIIS_M |
| Common GO terms | GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006366 - transcription by RNA polymerase II GO:0008270 - zinc ion binding |
| Homologous interactions | 8 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
