HitPredict

Interactor 1: SPA2 (P23201)
Protein SPA2
Gene: SPA2

Interactor 2: KEL1 (P38853)
Kelch repeat-containing protein 1
Gene: KEL1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.613

Property	Details
Experiments	18467557, 22615397
Identification Methods	protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005934 - cellular bud tip GO:0005935 - cellular bud neck GO:0005938 - cell cortex GO:0008360 - regulation of cell shape GO:0043332 - mating projection tip
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1466 Sc			1 1164
+	Sp
		145164 YF75_SCHPO (15-565): 3.01e-99: 335: 21.64		TEA3_SCHPO (273-1156): 2.04e-28: 126: 12.24
+	Hs
		848256 KMT2C_HUMAN (159-1322): 3.01e-27: 123: 8.86		HCFC1_HUMAN (96-463): 1.85e-71: 264: 22.17
+	Hs
		1243854 KMT2C_HUMAN (159-1322): 3.01e-27: 123: 8.86		HCFC2_HUMAN (113-623): 7.78e-71: 255: 17.90
+	Hs
		1344319 GIT1_HUMAN (38-493): 5.73e-27: 121: 16.56		KLHL1_HUMAN (171-490): 1.5e-51: 197: 13.62
+	Hs
		1057032 MDC1_HUMAN (77-1308): 2.17e-31: 136: 8.89		KLH20_HUMAN (250-487): 1.63e-38: 155: 14.64