HitPredict

Interactor 1: CNOT1 (A5YKK6)
CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1) (Negative regulator of transcription subunit 1 homolog) (NOT1H) (hNOT1)
Gene: CNOT1

Interactor 2: DDX6 (P26196)
Probable ATP-dependent RNA helicase DDX6 (EC 3.6.4.13) (ATP-dependent RNA helicase p54) (DEAD box protein 6) (Oncogene RCK)
Gene: DDX6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.825

The method score is based on:

Property	Details
Experiments	24768540, 29395067
Identification Methods	x-ray crystallography, affinity chromatography technology, pull down, proximity labelling technology
Interaction Type	association, physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	CNOT1_CAF1_bind~Helicase_C
Common GO terms	GO:0000932 - P-body GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0016020 - membrane and 2 others more... GO:0017148 - negative regulation of translation GO:0019904 - protein domain specific binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	2376
Hs

1	483

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024