Interactor 1: URE2 (P23202)
Transcriptional regulator URE2 (Disulfide reductase) (EC 1.8.4.-) (Glutathione peroxidase) (EC 1.11.1.9)
Gene: URE2

Interactor 2: URE2 (P23202)
Transcriptional regulator URE2 (Disulfide reductase) (EC 1.8.4.-) (Glutathione peroxidase) (EC 1.11.1.9)
Gene: URE2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 10388576, 10024516, 14610069, 17507672, 28650509, 17953455, 18324784, 18400756, 11342133, 18719252, 19345193, 19258323, 19040632, 21091436, 21497604, 22176525, 20057357
Identification Methods pull down, two hybrid, affinity chromatography technology, x-ray crystallography, fluorescent resonance energy transfer
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains GST_C~GST_C, GST_C~GST_N, GST_N~GST_N
Common GO terms GO:0003714 - transcription corepressor activity
GO:0004602 - glutathione peroxidase activity
GO:0005737 - cytoplasm
GO:0006808 - regulation of nitrogen utilization
GO:0010621 - negative regulation of transcription by transcription factor localization
and 3 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 354
Sc

1 354
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+ Zm
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+ At

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Last updated: 15 Jul 2024