Interactor 1: PGH1 (P23219)
Prostaglandin G/H synthase 1 (EC 1.14.99.1) (Cyclooxygenase-1) (COX-1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1) (Prostaglandin-endoperoxide synthase 1)
Gene: PTGS1

Interactor 2: PGH2 (P35354)
Prostaglandin G/H synthase 2 (EC 1.14.99.1) (Cyclooxygenase-2) (COX-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (Prostaglandin-endoperoxide synthase 2)
Gene: PTGS2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 18838483
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains An_peroxidase~An_peroxidase
Common GO terms GO:0001516 - prostaglandin biosynthetic process
GO:0004601 - peroxidase activity
GO:0004666 - prostaglandin-endoperoxide synthase activity
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
and 7 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 599
Hs

1 604
+ Mm
+ Hs

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Last updated: 15 Jul 2024