HitPredict

Interactor 1: SFPQ (P23246)
Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)
Gene: SFPQ

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21827211
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 707 Hs			1 245
+	Hs
		909516 PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		646864 PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		927003 PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		683319 PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		613403 SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Mm
		910319 SFPQ_MOUSE (230-707): 1.53e-70: 245: 98.95		1433E_MOUSE (2-243): 1.31e-144: 406: 63.53
+	Hs
		516444 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		909587 NONO_HUMAN (265-707): 1.49e-70: 239: 56.98		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Mm
		926857 SFPQ_MOUSE (230-707): 1.53e-70: 245: 98.95		1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00
+	Mm
		910328 NONO_MOUSE (233-707): 2.48e-67: 231: 55.04		1433E_MOUSE (2-243): 1.31e-144: 406: 63.53
+	Hs
		613347 SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		613399 SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		647104 MINK1_HUMAN (38-194): 2.38e-40: 161: 32.95		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		516374 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		683539 MINK1_HUMAN (38-194): 2.38e-40: 161: 32.95		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		684050 NONO_HUMAN (265-707): 1.49e-70: 239: 56.98		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		516440 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		904585 NONO_HUMAN (265-707): 1.49e-70: 239: 56.98		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		904923 PSPC1_HUMAN (230-707): 1.7e-60: 213: 51.96		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		684206 MINK1_HUMAN (38-194): 2.38e-40: 161: 32.95		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85