HitPredict

Interactor 1: CNOT1 (A5YKK6)
CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1) (Negative regulator of transcription subunit 1 homolog) (NOT1H) (hNOT1)
Gene: CNOT1

Interactor 2: NANO2 (P60321)
Nanos homolog 2 (NOS-2)
Gene: NANOS2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.681

Property	Details
Experiments	24736845, 28514442, 33961781
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0005634 - nucleus GO:0017148 - negative regulation of translation GO:1900153 - positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 2376 Hs			1 138
+	Mm
		888510 CNOT1_MOUSE (1-2376): 0: 3460: 99.16		NANO2_MOUSE (1-138): 3.39e-72: 213: 75.36
+	Hs
		61338 CNOT1_HUMAN (1-2376): 0: 3468: 100.00		NANO3_HUMAN (6-138): 2.01e-62: 190: 48.51
+	Hs
		61428 CNOT1_HUMAN (1-2376): 0: 3468: 100.00		NANO1_HUMAN (26-117): 1.34e-27: 104: 43.48
+	Dm
		91055 E2QCN4_DROME (1-2353): 0: 2855: 46.00		NANOS_DROME (61-115): 5.99e-27: 104: 52.73