HitPredict

Interactor 1: SFPQ (P23246)
Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)
Gene: SFPQ

Interactor 2: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.947

The method score is based on:

Property Details
Experiments 24981860, 35271311, 28514442, 33961781, 21819346, 37071682
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains NOPS~NOPS, NOPS~RRM_1, RRM_1~RRM_1
Common GO terms GO:0002218 - activation of innate immune response
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006355 - regulation of DNA-templated transcription
and 7 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 707
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024