HitPredict

Interactor 1: SFPQ (P23246)
Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)
Gene: SFPQ

Interactor 2: SIN3A (Q96ST3)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

The method score is based on:

Property	Details
Experiments	19339282, 21566083, 11259580
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0002218 - activation of innate immune response GO:0003677 - DNA binding GO:0003682 - chromatin binding and 6 others more... GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0042754 - negative regulation of circadian rhythm GO:0045892 - negative regulation of DNA-templated transcription GO:0048511 - rhythmic process
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	707
Hs

1	1273

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024