HitPredict

Interactor 1: SFPQ (P23246)
Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)
Gene: SFPQ

Interactor 2: DIDO1 (Q9BTC0)
Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1)
Gene: DIDO1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	28514442, 33961781, 30931476
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PHD~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 707 Hs			1 2240
+	Hs
		613628 SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00		PRC2C_HUMAN (27-1904): 3.9e-50: 199: 9.83
+	Hs
		832977 PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38		YLPM1_HUMAN (1365-2223): 2.36e-41: 170: 13.66
+	Hs
		516766 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		PRC2C_HUMAN (27-1904): 3.9e-50: 199: 9.83
+	Hs
		613377 SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00		YLPM1_HUMAN (1365-2223): 2.36e-41: 170: 13.66
+	Hs
		1263596 PSPC1_HUMAN (230-707): 1.7e-60: 213: 51.96		PRC2C_HUMAN (27-1904): 3.9e-50: 199: 9.83
+	Hs
		832987 NONO_HUMAN (265-707): 1.49e-70: 239: 56.98		YLPM1_HUMAN (1365-2223): 2.36e-41: 170: 13.66
+	Hs
		257670 PSPC1_HUMAN (230-707): 1.7e-60: 213: 51.96		ANR17_HUMAN (1108-2079): 3.68e-42: 173: 12.34
+	Hs
		833016 PSPC1_HUMAN (230-707): 1.7e-60: 213: 51.96		YLPM1_HUMAN (1365-2223): 2.36e-41: 170: 13.66
+	Hs
		1031405 PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38		TITIN_HUMAN (19-1290): 3.32e-21: 104: 10.49
+	Hs
		1069787 NONO_HUMAN (265-707): 1.49e-70: 239: 56.98		NSRP1_HUMAN (2033-2240): 4.74e-23: 108: 18.27
+	Hs
		516609 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		TITIN_HUMAN (19-1290): 3.32e-21: 104: 10.49
+	Hs
		516595 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		KMT2C_HUMAN (268-1949): 7.95e-19: 96.6: 10.24
+	Hs
		613619 SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00		SRRM2_HUMAN (6-1279): 6.35e-14: 80.3: 8.36
+	Hs
		613557 SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00		CIC_HUMAN (2-1657): 2.53e-13: 78.4: 7.87
+	Hs
		516749 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		SRRM2_HUMAN (6-1279): 6.35e-14: 80.3: 8.36
+	Hs
		1263533 PSPC1_HUMAN (230-707): 1.7e-60: 213: 51.96		NSRP1_HUMAN (2033-2240): 4.74e-23: 108: 18.27
+	Hs
		1069826 NONO_HUMAN (265-707): 1.49e-70: 239: 56.98		SRRM2_HUMAN (6-1279): 6.35e-14: 80.3: 8.36
+	Hs
		1069770 NONO_HUMAN (265-707): 1.49e-70: 239: 56.98		CIC_HUMAN (2-1657): 2.53e-13: 78.4: 7.87
+	Hs
		1288650 PABP5_HUMAN (244-545): 3.2e-43: 162: 15.34		SRRM2_HUMAN (6-1279): 6.35e-14: 80.3: 8.36
+	Hs
		1233564 MINK1_HUMAN (38-194): 2.38e-40: 161: 32.95		SRRM2_HUMAN (6-1279): 6.35e-14: 80.3: 8.36