HitPredict

Interactor 1: SFPQ (P23246)
Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)
Gene: SFPQ

Interactor 2: WWOX (Q9NZC7)
WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase) (Short chain dehydrogenase/reductase family 41C member 1)
Gene: WWOX

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.608

Property	Details
Experiments	16055720, 24550385
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0090575 - RNA polymerase II transcription regulator complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 707 Hs			1 414
+	Hs
		1031480 PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38		WWOX_HUMAN (1-414): 3.42e-136: 397: 100.00
+	Hs
		516721 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		WWOX_HUMAN (1-414): 3.42e-136: 397: 100.00
+	Hs
		1069812 NONO_HUMAN (265-707): 1.49e-70: 239: 56.98		WWOX_HUMAN (1-414): 3.42e-136: 397: 100.00
+	Hs
		1329986 PABP3_HUMAN (287-700): 9.1e-69: 239: 16.88		WWOX_HUMAN (1-414): 3.42e-136: 397: 100.00