HitPredict

Interactor 1: TBG1 (P23258)
Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1)
Gene: TUBG1

Interactor 2: KSYK (P43405)
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)
Gene: SYK

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16322234
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 451 Hs			1 635
+	Hs
		428078 TBB5_HUMAN (3-439): 0: 652: 33.79		KSYK_HUMAN (1-635): 0: 589: 100.00
+	Gg
		94429 TBB7_CHICK (3-439): 0: 652: 33.79		KSYK_CHICK (3-634): 0: 560: 76.27
+	Hs
		428077 TBB5_HUMAN (3-439): 0: 652: 33.79		ZAP70_HUMAN (6-635): 0: 535: 53.57
+	Hs
		381109 TBB4A_HUMAN (3-437): 0: 650: 33.49		FGFR1_HUMAN (179-635): 7.43e-116: 366: 26.24
+	Hs
		428109 TBB5_HUMAN (3-439): 0: 652: 33.79		EPHA4_HUMAN (329-626): 1.47e-105: 343: 34.54
+	Hs
		872702 TBB2B_HUMAN (3-440): 0: 652: 33.71		EPHA4_HUMAN (329-626): 1.47e-105: 343: 34.54
+	Hs
		872631 TBB4B_HUMAN (3-437): 0: 651: 33.95		EPHA4_HUMAN (329-626): 1.47e-105: 343: 34.54
+	Hs
		411549 TBB5_HUMAN (3-439): 0: 652: 33.79		LCK_HUMAN (5-201): 3.03e-71: 240: 23.29
+	Hs
		411668 TBB4B_HUMAN (3-437): 0: 651: 33.95		LCK_HUMAN (5-201): 3.03e-71: 240: 23.29
+	Hs
		427991 TBB5_HUMAN (3-439): 0: 652: 33.79		SRC_HUMAN (4-371): 2.15e-70: 239: 15.46
+	Hs
		614013 TBG1_HUMAN (1-451): 0: 655: 100.00		FAK1_HUMAN (344-626): 1.88e-57: 211: 39.30
+	Hs
		337936 TBG1_HUMAN (1-451): 0: 655: 100.00		EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15
+	Hs
		338386 TBB3_HUMAN (3-451): 0: 653: 33.11		EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15
+	Hs
		337782 TBB5_HUMAN (3-439): 0: 652: 33.79		EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15
+	Hs
		338266 TBB4B_HUMAN (3-437): 0: 651: 33.95		EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15
+	Hs
		337745 TBB4A_HUMAN (3-437): 0: 650: 33.49		EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15
+	Dm
		337680 TBB1_DROME (3-439): 0: 651: 34.48		SRC64_DROME (9-203): 3.92e-53: 192: 23.08
+	Hs
		428098 TBB5_HUMAN (3-439): 0: 652: 33.79		BLK_HUMAN (162-267): 2.8e-29: 123: 32.43
+	Hs
		428198 TBB5_HUMAN (3-439): 0: 652: 33.79		PTK6_HUMAN (14-200): 1.27e-14: 78.4: 20.87
+	Hs
		933801 TBB4B_HUMAN (3-437): 0: 651: 33.95		PTK6_HUMAN (14-200): 1.27e-14: 78.4: 20.87