HitPredict

Interactor 1: TBG1 (P23258)
Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1)
Gene: TUBG1

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	unassigned1853, 24725412
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005525 - GTP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043005 - neuron projection
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 451 Hs			1 2527
+	Hs
		1037252 TBB3_HUMAN (3-451): 0: 653: 33.11		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130537 TBB2B_HUMAN (3-440): 0: 652: 33.71		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		428247 TBB5_HUMAN (3-439): 0: 652: 33.79		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130508 TBA1C_HUMAN (3-451): 0: 651: 30.85		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		933841 TBB4B_HUMAN (3-437): 0: 651: 33.95		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		381221 TBB4A_HUMAN (3-437): 0: 650: 33.49		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1120842 Q53GA7_HUMAN (3-451): 0: 649: 30.85		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130529 TBB6_HUMAN (3-442): 0: 649: 33.56		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		933229 TBA1B_HUMAN (3-442): 0: 649: 31.25		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1046482 TBB2A_HUMAN (3-440): 0: 648: 33.71		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Mm
		1130127 TBB4A_MOUSE (3-437): 0: 650: 33.49		LRRK2_MOUSE (1-2527): 0: 2865: 86.09
+	Hs
		782771 TBA1B_HUMAN (3-442): 0: 649: 31.25		CSK_HUMAN (1722-2140): 2.25e-102: 339: 20.74
+	Hs
		1037439 TBB3_HUMAN (3-451): 0: 653: 33.11		SHOC2_HUMAN (944-1353): 1.23e-60: 222: 22.27
+	Hs
		428238 TBB5_HUMAN (3-439): 0: 652: 33.79		LRRK1_HUMAN (771-1194): 2.3e-35: 151: 16.38
+	Hs
		933832 TBB4B_HUMAN (3-437): 0: 651: 33.95		LRRK1_HUMAN (771-1194): 2.3e-35: 151: 16.38
+	Hs
		201179 TBB5_HUMAN (3-439): 0: 652: 33.79		M3K7_HUMAN (1869-2132): 8.36e-23: 107: 28.83
+	Hs
		201419 TBB2B_HUMAN (3-440): 0: 652: 33.71		M3K7_HUMAN (1869-2132): 8.36e-23: 107: 28.83
+	Hs
		201171 TBB4A_HUMAN (3-437): 0: 650: 33.49		M3K7_HUMAN (1869-2132): 8.36e-23: 107: 28.83