Interactor 1: CNOT1 (A5YKK6)
CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1) (Negative regulator of transcription subunit 1 homolog) (NOT1H) (hNOT1)
Gene: CNOT1

Interactor 2: CNOT2 (Q9NZN8)
CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2)
Gene: CNOT2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.961

The method score is based on:

Property Details
Experiments 16778766, 26496610, 27173435, 29395067, 10637334, 34887419, 11805826
Identification Methods affinity chromatography technology, proximity labelling technology, two hybrid, tandem affinity purification, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains NOT2_3_5~Not1
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 - P-body
GO:0001829 - trophectodermal cell differentiation
GO:0005634 - nucleus
and 7 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 2376
Hs

1 540
+ Mm
+ Hs
+ Dm
+ Dm
+ Sc
+ Sc

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Last updated: 15 Jul 2024