Interactor 1: CNOT1 (A5YKK6)
CCR4-NOT transcription complex subunit 1 (CCR4-associated factor 1) (Negative regulator of transcription subunit 1 homolog) (NOT1H) (hNOT1)
Gene: CNOT1

Interactor 2: CNOT8 (Q9UFF9)
CCR4-NOT transcription complex subunit 8 (EC 3.1.13.4) (CAF1-like protein) (CALIFp) (CAF2) (CCR4-associated factor 8) (Caf1b)
Gene: CNOT8

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.950

The method score is based on:

Property Details
Experiments 16778766, 17353931, 26496610, 10637334, 34887419, 22977175
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CAF1~CNOT1_CAF1_bind
Common GO terms GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 - P-body
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005829 - cytosol
and 4 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 2376
Hs

1 292
+ Hs
+ Mm
+ Dm
+ Dm
+ Dm
+ Sp
+ Sc
+ Ce

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Last updated: 15 Jul 2024