HitPredict

Interactor 1: A5YM63 (A5YM63)
Neurofilament medium polypeptide (160 kDa neurofilament protein) (Neurofilament 3) (Neurofilament triplet M protein)
Gene: NEFM

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned1853
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030424 - axon
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 877 Hs			1 2527
+	Hs
		3119 A0A0S2Z428_HUMAN (67-411): 7.62e-92: 303: 30.46		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130818 V9HWE1_HUMAN (8-413): 2.42e-76: 258: 44.61		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		443567 VIME_HUMAN (8-413): 2.42e-76: 258: 44.61		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		422196 NFL_HUMAN (74-420): 1.48e-72: 250: 53.16		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		72923 B4DN72_HUMAN (1-420): 1.03e-69: 240: 27.77		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130283 K2C73_HUMAN (2-415): 4.35e-66: 232: 29.91		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		531584 K2C5_HUMAN (67-415): 3.26e-56: 206: 29.55		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		380486 K2C6B_HUMAN (67-415): 2.76e-56: 205: 30.11		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		724862 MYH9_HUMAN (487-876): 3.79e-14: 79.1: 9.49		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130714 MYH2_HUMAN (428-877): 3.16e-13: 76.4: 12.12		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		725175 MYH10_HUMAN (570-877): 3.66e-11: 69.4: 10.61		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Mm
		1130117 MYH9_MOUSE (49-519): 7.75e-15: 81.4: 9.53		LRRK2_MOUSE (1-2527): 0: 2865: 86.09