Interactor 1: SYWC (P23381)
Tryptophan--tRNA ligase, cytoplasmic (EC 6.1.1.2) (Interferon-induced protein 53) (IFP53) (Tryptophanyl-tRNA synthetase) (TrpRS) (hWRS) [Cleaved into: T1-TrpRS; T2-TrpRS]
Gene: WARS1

Interactor 2: SYWC (P23381)
Tryptophan--tRNA ligase, cytoplasmic (EC 6.1.1.2) (Interferon-induced protein 53) (IFP53) (Tryptophanyl-tRNA synthetase) (TrpRS) (hWRS) [Cleaved into: T1-TrpRS; T2-TrpRS]
Gene: WARS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 17637340
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains tRNA-synt_1b~tRNA-synt_1b, WHEP-TRS~tRNA-synt_1b
Common GO terms GO:0001525 - angiogenesis
GO:0004830 - tryptophan-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 14 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 471
Hs

1 471
+ Gs
+ Mp
+ Hs
+ Cj
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024