HitPredict

Interactor 1: RS3 (P23396)
Small ribosomal subunit protein uS3 (40S ribosomal protein S3) (EC 4.2.99.18)
Gene: RPS3

Interactor 2: LIN41 (Q2Q1W2)
E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71)
Gene: TRIM71

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0017148 - negative regulation of translation
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 243 Hs			1 868
+	Hs
		616294 RS3_HUMAN (1-243): 8.64e-116: 332: 100.00		TIF1B_HUMAN (195-490): 1.02e-84: 290: 25.25
+	Hs
		616505 RS3_HUMAN (1-243): 8.64e-116: 332: 100.00		TRIM6_HUMAN (185-599): 1.09e-85: 283: 11.93
+	Hs
		170257 RS3_HUMAN (1-243): 8.64e-116: 332: 100.00		TIF1A_HUMAN (71-606): 4.56e-80: 281: 17.15
+	Hs
		616382 RS3_HUMAN (1-243): 8.64e-116: 332: 100.00		TRI67_HUMAN (50-571): 1.02e-71: 253: 16.47
+	Hs
		175640 RS3_HUMAN (1-243): 8.64e-116: 332: 100.00		TRI18_HUMAN (53-513): 8.52e-63: 226: 16.21