Interactor 1: KS6B1 (P23443)
Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)
Gene: RPS6KB1

Interactor 2: PDIP3 (Q9BY77)
Polymerase delta-interacting protein 3 (46 kDa DNA polymerase delta interaction protein) (p46) (S6K1 Aly/REF-like target) (SKAR)
Gene: POLDIP3

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.815

The method score is based on:

Property Details
Experiments 15341740, 18423201
Identification Methods affinity chromatography technology, two hybrid, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~RRM_1
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0045727 - positive regulation of translation
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 525
Hs

1 421
+ Hs
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024