HitPredict

Interactor 1: JAK1 (P23458)
Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)
Gene: JAK1

Interactor 2: HAVR2 (Q8TDQ0)
Hepatitis A virus cellular receptor 2 (HAVcr-2) (T-cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T-cell immunoglobulin mucin receptor 3) (TIM-3) (T-cell membrane protein 3) (CD antigen CD366)
Gene: HAVCR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1154 Hs			1 301
+	Hs
		411802 LCK_HUMAN (833-1153): 1.23e-96: 319: 30.44		HAVR2_HUMAN (1-301): 0: 542: 100.00
+	Hs
		412276 FYN_HUMAN (843-1151): 5.82e-96: 318: 27.74		HAVR2_HUMAN (1-301): 0: 542: 100.00
+	Hs
		669189 TYK2_HUMAN (867-1152): 1.57e-32: 139: 19.00		HAVR2_HUMAN (1-301): 0: 542: 100.00
+	Hs
		796479 ZAP70_HUMAN (614-841): 8.24e-17: 87.4: 28.75		HAVR2_HUMAN (1-301): 0: 542: 100.00
+	Hs
		412298 FYN_HUMAN (843-1151): 5.82e-96: 318: 27.74		HAVR1_HUMAN (10-133): 2.47e-51: 174: 40.95