HitPredict

Interactor 1: PTPRB (P23467)
Receptor-type tyrosine-protein phosphatase beta (Protein-tyrosine phosphatase beta) (R-PTP-beta) (EC 3.1.3.48) (Vascular endothelial protein tyrosine phosphatase) (VE-PTP)
Gene: PTPRB

Interactor 2: WASP (P42768)
Actin nucleation-promoting factor WAS (Wiskott-Aldrich syndrome protein) (WASp)
Gene: WAS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	19167335
Identification Methods	phosphatase assay
Interaction Type	dephosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1997 Hs			1 502
+	Hs
		441188 PTPRC_HUMAN (1703-1975): 3.32e-25: 117: 27.67		WASP_HUMAN (1-487): 8.09e-99: 308: 100.00
+	Hs
		790677 PTPRO_HUMAN (41-479): 4.06e-24: 113: 14.46		WASP_HUMAN (1-487): 8.09e-99: 308: 100.00
+	Hs
		617160 PTPRZ_HUMAN (1703-1976): 2.1e-23: 111: 30.96		WASP_HUMAN (1-487): 8.09e-99: 308: 100.00
+	Hs
		617086 PTPRG_HUMAN (1727-1968): 6.3e-23: 109: 29.60		WASP_HUMAN (1-487): 8.09e-99: 308: 100.00
+	Hs
		490001 PTPRF_HUMAN (905-1707): 2.85e-67: 255: 10.82		CBP_HUMAN (107-498): 6.15e-40: 156: 13.65
+	Hs
		790667 PTPRJ_HUMAN (1245-1617): 2.86e-16: 87.8: 15.75		WASP_HUMAN (1-487): 8.09e-99: 308: 100.00
+	Hs
		362950 FINC_HUMAN (1147-1761): 1.77e-33: 144: 15.13		DYN2_HUMAN (244-438): 9.39e-25: 110: 17.54
+	Hs
		363240 FINC_HUMAN (1147-1761): 1.77e-33: 144: 15.13		TITIN_HUMAN (216-486): 6.08e-22: 102: 14.39
+	Hs
		1137771 TITIN_HUMAN (903-1102): 2.88e-09: 65: 11.52		OBSCN_HUMAN (150-494): 2.35e-26: 115: 15.43
+	Hs
		1264771 TITIN_HUMAN (903-1102): 2.88e-09: 65: 11.52		TITIN_HUMAN (216-486): 6.08e-22: 102: 14.39