HitPredict

Interactor 1: PTPRB (P23467)
Receptor-type tyrosine-protein phosphatase beta (Protein-tyrosine phosphatase beta) (R-PTP-beta) (EC 3.1.3.48) (Vascular endothelial protein tyrosine phosphatase) (VE-PTP)
Gene: PTPRB

Interactor 2: CNTN1 (Q12860)
Contactin-1 (Glycoprotein gp135) (Neural cell surface protein F3)
Gene: CNTN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	9049255, 7628014
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	fn3~fn3, I-set~fn3, fn3~ig, Ig_3~fn3
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1997 Hs			1 1018
+	Hs
		616927 PTPRB_HUMAN (1-1997): 0: 1320: 100.00		NRCAM_HUMAN (3-791): 4.09e-62: 233: 15.33
+	Gg
		47583 A0A8V0YWD3_CHICK (1687-1966): 1.6e-103: 356: 35.23		CNTN1_CHICK (1-1000): 0: 666: 77.20
+	Hs
		617163 PTPRZ_HUMAN (1703-1976): 2.1e-23: 111: 30.96		CNTN1_HUMAN (1-1018): 0: 696: 100.00
+	Mm
		1167061 SDK2_MOUSE (456-1709): 5.41e-91: 332: 10.89		SDK2_MOUSE (279-992): 4.79e-47: 186: 15.29
+	Mm
		56906 PTPRA_MOUSE (1683-1966): 1.22e-48: 190: 35.29		PTPRF_MOUSE (3-974): 7.47e-85: 303: 14.38
+	Hs
		131993 PTPRA_HUMAN (1687-1966): 2.17e-103: 353: 35.23		NCHL1_HUMAN (2-591): 1.29e-32: 139: 12.38
+	Mm
		1167062 SDK2_MOUSE (456-1709): 5.41e-91: 332: 10.89		DSCAM_MOUSE (3-722): 2.68e-32: 138: 12.19
+	Mm
		93891 SDK2_MOUSE (456-1709): 5.41e-91: 332: 10.89		E9QPR7_MOUSE (3-727): 5.8e-25: 114: 12.52
+	Mm
		1322320 DSCAM_MOUSE (2-574): 2.99e-54: 212: 10.92		DSCAM_MOUSE (3-722): 2.68e-32: 138: 12.19
+	Dr
		47534 A0A8M1RL98_DANRE (1685-1979): 2.53e-22: 107: 27.36		A4JYP8_DANRE (2-800): 7.38e-63: 233: 14.47
+	Dr
		60061 B8A5J4_DANRE (1716-1979): 3.92e-22: 106: 28.57		A4JYP8_DANRE (2-800): 7.38e-63: 233: 14.47
+	Hs
		489886 PTPRF_HUMAN (905-1707): 2.85e-67: 255: 10.82		PTPRF_HUMAN (44-332): 2.53e-12: 73.6: 25.64
+	Mm
		93892 DSCAM_MOUSE (2-574): 2.99e-54: 212: 10.92		E9QPR7_MOUSE (3-727): 5.8e-25: 114: 12.52
+	Mm
		574004 PTPRA_MOUSE (1683-1966): 1.22e-48: 190: 35.29		NCHL1_MOUSE (2-593): 7.58e-31: 133: 11.84
+	Mm
		93890 E9QPR7_MOUSE (1-574): 2.29e-51: 203: 11.55		E9QPR7_MOUSE (3-727): 5.8e-25: 114: 12.52
+	Hs
		489969 PTPRO_HUMAN (41-479): 4.06e-24: 113: 14.46		PTPRF_HUMAN (44-332): 2.53e-12: 73.6: 25.64
+	Hs
		489902 PTPRZ_HUMAN (1703-1976): 2.1e-23: 111: 30.96		PTPRF_HUMAN (44-332): 2.53e-12: 73.6: 25.64