HitPredict

Interactor 1: PTPRB (P23467)
Receptor-type tyrosine-protein phosphatase beta (Protein-tyrosine phosphatase beta) (R-PTP-beta) (EC 3.1.3.48) (Vascular endothelial protein tyrosine phosphatase) (VE-PTP)
Gene: PTPRB

Interactor 2: GAB1 (Q13480)
GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1)
Gene: GAB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	19167335
Identification Methods	phosphatase assay
Interaction Type	dephosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001525 - angiogenesis
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1997 Hs			1 694
+	Hs
		577020 PTPRA_HUMAN (1687-1966): 2.17e-103: 353: 35.23		GAB1_HUMAN (1-694): 0: 547: 100.00
+	Hs
		441197 PTPRC_HUMAN (1703-1975): 3.32e-25: 117: 27.67		GAB1_HUMAN (1-694): 0: 547: 100.00
+	Hs
		1035378 PTPRO_HUMAN (41-479): 4.06e-24: 113: 14.46		GAB1_HUMAN (1-694): 0: 547: 100.00
+	Hs
		617108 PTPRG_HUMAN (1727-1968): 6.3e-23: 109: 29.60		GAB1_HUMAN (1-694): 0: 547: 100.00
+	Hs
		1020092 PTPRJ_HUMAN (1245-1617): 2.86e-16: 87.8: 15.75		GAB1_HUMAN (1-694): 0: 547: 100.00
+	Mm
		1194483 TENR_MOUSE (1333-1595): 3.14e-11: 71.1: 12.11		CNKR2_MOUSE (7-393): 1.86e-56: 210: 16.38