HitPredict

Interactor 1: PTPRB (P23467)
Receptor-type tyrosine-protein phosphatase beta (Protein-tyrosine phosphatase beta) (R-PTP-beta) (EC 3.1.3.48) (Vascular endothelial protein tyrosine phosphatase) (VE-PTP)
Gene: PTPRB

Interactor 2: NRCAM (Q92823)
Neuronal cell adhesion molecule (Nr-CAM) (Neuronal surface protein Bravo) (hBravo) (NgCAM-related cell adhesion molecule) (Ng-CAM-related)
Gene: NRCAM

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	9049255
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	fn3~fn3, I-set~fn3, Ig_3~fn3
Common GO terms	GO:0001525 - angiogenesis GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1997 Hs			1 1304
+	Hs
		616914 PTPRB_HUMAN (1-1997): 0: 1320: 100.00		CNTN1_HUMAN (323-1179): 8.31e-74: 268: 14.77
+	Gg
		47583 A0A8V0YWD3_CHICK (1687-1966): 1.6e-103: 356: 35.23		CNTN1_CHICK (2-938): 2.35e-97: 337: 15.79
+	Hs
		131993 PTPRA_HUMAN (1687-1966): 2.17e-103: 353: 35.23		NCHL1_HUMAN (4-730): 6.13e-49: 193: 15.49
+	Mm
		93891 SDK2_MOUSE (456-1709): 5.41e-91: 332: 10.89		E9QPR7_MOUSE (4-955): 1.17e-54: 212: 12.30
+	Mm
		1167062 SDK2_MOUSE (456-1709): 5.41e-91: 332: 10.89		DSCAM_MOUSE (4-861): 1.2e-49: 196: 12.61
+	Mm
		574004 PTPRA_MOUSE (1683-1966): 1.22e-48: 190: 35.29		NCHL1_MOUSE (6-976): 8.1e-85: 304: 16.21
+	Mm
		1167061 SDK2_MOUSE (456-1709): 5.41e-91: 332: 10.89		SDK2_MOUSE (736-1178): 7.02e-20: 99.1: 9.87
+	Mm
		93892 DSCAM_MOUSE (2-574): 2.99e-54: 212: 10.92		E9QPR7_MOUSE (4-955): 1.17e-54: 212: 12.30
+	Mm
		93890 E9QPR7_MOUSE (1-574): 2.29e-51: 203: 11.55		E9QPR7_MOUSE (4-955): 1.17e-54: 212: 12.30
+	Mm
		1322320 DSCAM_MOUSE (2-574): 2.99e-54: 212: 10.92		DSCAM_MOUSE (4-861): 1.2e-49: 196: 12.61
+	Mm
		1112510 SDK1_MOUSE (4-212): 9.12e-19: 96.2: 15.79		SDK1_MOUSE (130-1295): 3.89e-77: 284: 15.67
+	Hs
		617163 PTPRZ_HUMAN (1703-1976): 2.1e-23: 111: 30.96		CNTN1_HUMAN (323-1179): 8.31e-74: 268: 14.77
+	Mm
		936322 DSCAM_MOUSE (2-574): 2.99e-54: 212: 10.92		DCC_MOUSE (3-781): 2.31e-31: 136: 13.01
+	Hs
		363240 FINC_HUMAN (1147-1761): 1.77e-33: 144: 15.13		TITIN_HUMAN (519-838): 1.05e-12: 75.6: 12.15
+	Dr
		47534 A0A8M1RL98_DANRE (1685-1979): 2.53e-22: 107: 27.36		A4JYP8_DANRE (12-477): 1.85e-13: 77.4: 9.80
+	Dr
		60061 B8A5J4_DANRE (1716-1979): 3.92e-22: 106: 28.57		A4JYP8_DANRE (12-477): 1.85e-13: 77.4: 9.80
+	Hs
		1264771 TITIN_HUMAN (903-1102): 2.88e-09: 65: 11.52		TITIN_HUMAN (519-838): 1.05e-12: 75.6: 12.15