HitPredict

Interactor 1: PTPRD (P23468)
Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48)
Gene: PTPRD

Interactor 2: LIPA1 (Q13136)
Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)
Gene: PPFIA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.786

Property	Details
Experiments	9624153, 8524829
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SAM_1~Y_phosphatase
Common GO terms	GO:0098685 - Schaffer collateral - CA1 synapse
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1912 Hs			1 1202
+	Hs
		1025279 PTPRS_HUMAN (1-1912): 0: 1555: 71.33		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		259637 PTPRD_HUMAN (1-1912): 0: 1640: 100.00		LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82
+	Hs
		489956 PTPRF_HUMAN (1-1912): 0: 1497: 67.03		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		259643 PTPRS_HUMAN (1-1912): 0: 1555: 71.33		LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82
+	Hs
		259635 PTPRF_HUMAN (1-1912): 0: 1497: 67.03		LIPA2_HUMAN (35-1202): 3.45e-130: 431: 62.82
+	Hs
		255236 PTPRD_HUMAN (1-1912): 0: 1640: 100.00		LIPA3_HUMAN (1-265): 3.37e-12: 73.2: 12.45
+	Hs
		255244 PTPRS_HUMAN (1-1912): 0: 1555: 71.33		LIPA3_HUMAN (1-265): 3.37e-12: 73.2: 12.45
+	Hs
		255234 PTPRF_HUMAN (1-1912): 0: 1497: 67.03		LIPA3_HUMAN (1-265): 3.37e-12: 73.2: 12.45
+	Dm
		65322 LAR_DROME (13-1352): 5.19e-168: 566: 33.33		A8DYM0_DROME (860-1122): 3.71e-105: 360: 42.21
+	Dm
		114417 LAR_DROME (13-1352): 5.19e-168: 566: 33.33		M9PCD4_DROME (3-277): 4.35e-10: 66.3: 12.59
+	Dm
		561777 LAR_DROME (13-1352): 5.19e-168: 566: 33.33		Q9VM93_DROME (3-277): 1.13e-09: 65.1: 12.59