HitPredict

Interactor 1: PTPRD (P23468)
Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48)
Gene: PTPRD

Interactor 2: PTPRS (Q13332)
Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma)
Gene: PTPRS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.800

The method score is based on:

Property Details
Experiments 28675297, 9566880
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains fn3~fn3, I-set~fn3, Ig_3~fn3, I-set~I-set, Ig_3~I-set, Ig_3~Ig_3, Y_phosphatase~Y_phosphatase
Common GO terms GO:0004725 - protein tyrosine phosphatase activity
GO:0005886 - plasma membrane
GO:0006470 - protein dephosphorylation
GO:0042734 - presynaptic membrane
GO:0043235 - receptor complex
and 6 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1912
Hs

1 1948
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Last updated: 15 Jul 2024