HitPredict

Interactor 1: PTPRD (P23468)
Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48)
Gene: PTPRD

Interactor 2: DSC3 (Q14574)
Desmocollin-3 (Cadherin family member 3) (Desmocollin-4) (HT-CP)
Gene: DSC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27880917
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1912 Hs			1 896
+	Hs
		617035 PTPRD_HUMAN (1-1912): 0: 1640: 100.00		PCDG6_HUMAN (1-818): 0: 732: 18.48
+	Hs
		617033 PTPRD_HUMAN (1-1912): 0: 1640: 100.00		PCDB6_HUMAN (1-475): 2.05e-84: 289: 15.96
+	Hs
		617032 PTPRD_HUMAN (1-1912): 0: 1640: 100.00		PCDGG_HUMAN (2-464): 7.56e-83: 287: 16.98
+	Hs
		617023 PTPRD_HUMAN (1-1912): 0: 1640: 100.00		PCDBG_HUMAN (2-485): 6.43e-82: 282: 16.27
+	Hs
		521727 PTPRD_HUMAN (1-1912): 0: 1640: 100.00		CADH1_HUMAN (2-464): 1.66e-38: 157: 15.98
+	Hs
		490028 PTPRF_HUMAN (1-1912): 0: 1497: 67.03		PCDBG_HUMAN (2-485): 6.43e-82: 282: 16.27
+	Rn
		1145482 PTPRF_RAT (1-1912): 0: 1502: 66.46		CADH2_RAT (2-385): 7.38e-56: 210: 18.23
+	Hs
		521907 PTPRS_HUMAN (1-1912): 0: 1555: 71.33		CADH1_HUMAN (2-464): 1.66e-38: 157: 15.98
+	Hs
		1032046 PTPRS_HUMAN (1-1912): 0: 1555: 71.33		PCDGD_HUMAN (1-235): 3.77e-29: 127: 14.34
+	Hs
		489891 PTPRF_HUMAN (1-1912): 0: 1497: 67.03		CADH1_HUMAN (2-464): 1.66e-38: 157: 15.98
+	Hs
		1031982 PTPRS_HUMAN (1-1912): 0: 1555: 71.33		DSG2_HUMAN (69-391): 3.52e-20: 98.5: 17.85
+	Hs
		490044 PTPRF_HUMAN (1-1912): 0: 1497: 67.03		PCDGD_HUMAN (1-235): 3.77e-29: 127: 14.34
+	Hs
		576981 PTPRA_HUMAN (1125-1912): 0: 804: 39.72		CADH2_HUMAN (2-385): 2.16e-54: 205: 17.55
+	Hs
		580201 PTPRG_HUMAN (833-1909): 0: 716: 25.56		CADH2_HUMAN (2-385): 2.16e-54: 205: 17.55
+	Hs
		521728 PTPRG_HUMAN (833-1909): 0: 716: 25.56		CADH1_HUMAN (2-464): 1.66e-38: 157: 15.98
+	Hs
		580229 PTPRJ_HUMAN (1615-1909): 2.71e-107: 377: 37.29		CADH2_HUMAN (2-385): 2.16e-54: 205: 17.55
+	Hs
		521898 PTPRJ_HUMAN (1615-1909): 2.71e-107: 377: 37.29		CADH1_HUMAN (2-464): 1.66e-38: 157: 15.98
+	Hs
		441173 PTPRC_HUMAN (441-1637): 1.31e-85: 311: 15.79		CADH2_HUMAN (2-385): 2.16e-54: 205: 17.55
+	Mm
		1351667 S4R1M0_MOUSE (623-1641): 1.26e-84: 305: 16.11		CAD17_MOUSE (185-606): 2.53e-24: 111: 28.67
+	Hs
		1123263 SDK2_HUMAN (22-921): 3.85e-77: 287: 18.09		PCDGD_HUMAN (1-235): 3.77e-29: 127: 14.34