HitPredict

Interactor 1: PTPRD (P23468)
Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48)
Gene: PTPRD

Interactor 2: LRRN1 (Q6UXK5)
Leucine-rich repeat neuronal protein 1 (Neuronal leucine-rich repeat protein 1) (NLRR-1)
Gene: LRRN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	I-set~fn3, I-set~I-set, I-set~LRR_8, Ig_3~I-set, Ig_3~LRR_8
Common GO terms	GO:0051965 - positive regulation of synapse assembly
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1912 Hs			1 716
+	Hs
		259496 PTPRD_HUMAN (1-1912): 0: 1640: 100.00		LRRN2_HUMAN (4-618): 1.16e-111: 355: 53.07
+	Hs
		616988 PTPRD_HUMAN (1-1912): 0: 1640: 100.00		LIGO2_HUMAN (4-574): 7.88e-87: 287: 24.33
+	Hs
		1069932 PTPRK_HUMAN (60-687): 3.27e-16: 87.4: 15.18		LRIG3_HUMAN (43-715): 3.24e-82: 284: 15.35
+	Hs
		1069962 PTPRK_HUMAN (60-687): 3.27e-16: 87.4: 15.18		LRIG1_HUMAN (17-701): 1.57e-73: 260: 15.05