Interactor 1: SP100 (P23497)
Nuclear autoantigen Sp-100 (Nuclear dot-associated Sp100 protein) (Speckled 100 kDa)
Gene: SP100

Interactor 2: CREM (Q03060)
cAMP-responsive element modulator (Inducible cAMP early repressor) (ICER)
Gene: CREM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 0.60 0.541

The method score is based on:

Property Details
Experiments 21988832
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 2 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 879
Hs

1 345
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Dm
+ Dm
+ Dm

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Last updated: 15 Jul 2024