HitPredict

Interactor 1: A6H8W8 (A6H8W8)
Intersectin 2
Gene: ITSN2

Interactor 2: EPS15 (P42566)
Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p)
Gene: EPS15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned2213
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0005737 - cytoplasm GO:0006897 - endocytosis
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1669 Hs			1 896
+	Hs
		787985 ITSN2_HUMAN (1-1669): 0: 862: 98.35		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Hs
		787920 ITSN1_HUMAN (1-1665): 0: 780: 56.87		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Cl
		47357 F1PHV6_CANLF (1-1665): 0: 793: 56.82		A0A8I3PJA6_CANLF (1-896): 5.87e-149: 464: 92.91
+	Mm
		788010 ITSN1_MOUSE (1-1665): 0: 777: 57.10		EPS15_MOUSE (1-896): 6.54e-132: 419: 88.54
+	Hs
		1349275 ITSN2_HUMAN (1-1669): 0: 862: 98.35		ITSN2_HUMAN (3-845): 2.31e-61: 229: 14.40
+	Hs
		1078919 ITSN2_HUMAN (1-1669): 0: 862: 98.35		ITSN1_HUMAN (2-520): 3.13e-38: 157: 14.61
+	Hs
		61738 A6H8W8_HUMAN (1-1669): 0: 873: 100.00		EP15R_HUMAN (417-891): 5.86e-14: 78.3: 11.98
+	Hs
		1349279 ITSN2_HUMAN (1-1669): 0: 862: 98.35		EP15R_HUMAN (417-891): 5.86e-14: 78.3: 11.98
+	Hs
		1078828 ITSN1_HUMAN (1-1665): 0: 780: 56.87		ITSN1_HUMAN (2-520): 3.13e-38: 157: 14.61
+	Hs
		259644 ITSN1_HUMAN (1-1665): 0: 780: 56.87		LIPA2_HUMAN (210-884): 2.13e-31: 134: 11.53
+	Rn
		92844 ITSN1_RAT (1-1665): 0: 771: 56.56		E9PSY8_RAT (9-333): 4.64e-17: 88.3: 11.66
+	Hs
		1078923 ITSN1_HUMAN (1-1665): 0: 780: 56.87		EP15R_HUMAN (417-891): 5.86e-14: 78.3: 11.98
+	Mm
		1141846 ITSN1_MOUSE (1-1665): 0: 777: 57.10		EP15R_MOUSE (417-895): 9.06e-11: 67.9: 12.27
+	Hs
		506537 BCR_HUMAN (746-1668): 6.74e-67: 251: 12.83		EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00
+	Rn
		957077 KALRN_RAT (114-1582): 3.78e-80: 297: 12.94		MRCKB_RAT (227-886): 5.86e-43: 172: 11.89
+	Hs
		1078876 PREX1_HUMAN (1139-1566): 9.29e-71: 265: 19.28		ITSN1_HUMAN (2-520): 3.13e-38: 157: 14.61
+	Ce
		105247 G5ECK4_CAEEL (833-1632): 1.42e-72: 270: 15.28		Q9BIF4_CAEEL (7-213): 5.25e-19: 94.5: 37.55
+	Ce
		1308360 Q9BIF4_CAEEL (91-736): 3.33e-25: 115: 15.84		Q9U2T9_CAEEL (5-425): 1.07e-23: 109: 11.85