HitPredict

Interactor 1: SP100 (P23497)
Nuclear autoantigen Sp-100 (Nuclear dot-associated Sp100 protein) (Speckled 100 kDa)
Gene: SP100

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	31753913
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 879 Hs			1 618
+	Hs
		818229 SOX2_HUMAN (736-852): 3.75e-28: 117: 15.39		MIRO1_HUMAN (1-618): 0: 763: 59.65
+	Zm
		34123 Q5NKN3_MAIZE (732-849): 4.27e-27: 110: 41.18		A0A1D6L934_MAIZE (2-618): 0: 635: 36.56
+	Hs
		449625 HMGB1_HUMAN (675-847): 9.29e-36: 136: 76.30		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		449660 HMGB1_HUMAN (675-847): 9.29e-36: 136: 76.30		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		175768 HMGB3_HUMAN (675-855): 1.68e-34: 132: 54.70		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		70545 HGB1A_HUMAN (675-847): 4.47e-33: 129: 72.83		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		817897 SOX2_HUMAN (736-852): 3.75e-28: 117: 15.39		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		567665 UBF1_HUMAN (684-878): 1.22e-16: 86.7: 22.56		RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22
+	Ce
		136794 UNC89_CAEEL (427-879): 4.14e-14: 79.4: 11.77		CDC42_CAEEL (3-186): 8.66e-76: 241: 24.24
+	Ce
		104464 UNC89_CAEEL (427-879): 4.14e-14: 79.4: 11.77		G5EBV3_CAEEL (3-186): 3.6e-74: 237: 23.23
+	Ce
		136793 UNC89_CAEEL (427-879): 4.14e-14: 79.4: 11.77		RAC1_CAEEL (3-177): 2.15e-73: 235: 25.40
+	Hs
		817886 SOX2_HUMAN (736-852): 3.75e-28: 117: 15.39		RAB1A_HUMAN (416-593): 1.56e-40: 148: 18.28
+	Hs
		817852 SOX2_HUMAN (736-852): 3.75e-28: 117: 15.39		RAB8A_HUMAN (411-594): 7.98e-27: 110: 15.34
+	Hs
		914010 TFAM_HUMAN (683-859): 1.46e-29: 120: 18.18		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		817882 SOX2_HUMAN (736-852): 3.75e-28: 117: 15.39		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		178915 TOX3_HUMAN (765-839): 6.78e-22: 103: 38.67		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		996905 SSRP1_HUMAN (642-837): 4.16e-29: 126: 22.57		RHOF_HUMAN (2-167): 3.37e-11: 65.1: 26.67
+	Hs
		120407 SSRP1_HUMAN (642-837): 4.16e-29: 126: 22.57		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		817864 SOX2_HUMAN (736-852): 3.75e-28: 117: 15.39		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		299611 TOX_HUMAN (765-849): 3.13e-17: 88.1: 37.65		RHOF_HUMAN (2-167): 3.37e-11: 65.1: 26.67