HitPredict

Interactor 1: A6H8W8 (A6H8W8)
Intersectin 2
Gene: ITSN2

Interactor 2: EP15R (Q9UBC2)
Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R)
Gene: EPS15L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned2213
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0005737 - cytoplasm GO:0006897 - endocytosis
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1669 Hs			1 864
+	Hs
		1349279 ITSN2_HUMAN (1-1669): 0: 862: 98.35		EP15R_HUMAN (1-864): 1.18e-150: 466: 100.00
+	Hs
		61732 A6H8W8_HUMAN (1-1669): 0: 873: 100.00		EPS15_HUMAN (1-862): 3.59e-115: 374: 42.20
+	Hs
		1078923 ITSN1_HUMAN (1-1665): 0: 780: 56.87		EP15R_HUMAN (1-864): 1.18e-150: 466: 100.00
+	Hs
		787985 ITSN2_HUMAN (1-1669): 0: 862: 98.35		EPS15_HUMAN (1-862): 3.59e-115: 374: 42.20
+	Mm
		1141846 ITSN1_MOUSE (1-1665): 0: 777: 57.10		EP15R_MOUSE (1-862): 1.06e-124: 399: 92.11
+	Hs
		787920 ITSN1_HUMAN (1-1665): 0: 780: 56.87		EPS15_HUMAN (1-862): 3.59e-115: 374: 42.20
+	Cl
		47357 F1PHV6_CANLF (1-1665): 0: 793: 56.82		A0A8I3PJA6_CANLF (1-862): 1.93e-105: 348: 41.45
+	Mm
		788010 ITSN1_MOUSE (1-1665): 0: 777: 57.10		EPS15_MOUSE (1-862): 8.21e-97: 325: 41.30
+	Hs
		1078919 ITSN2_HUMAN (1-1669): 0: 862: 98.35		ITSN1_HUMAN (1-522): 2.39e-32: 138: 13.31
+	Hs
		1349275 ITSN2_HUMAN (1-1669): 0: 862: 98.35		ITSN2_HUMAN (2-531): 1.52e-24: 112: 11.86
+	Hs
		1078828 ITSN1_HUMAN (1-1665): 0: 780: 56.87		ITSN1_HUMAN (1-522): 2.39e-32: 138: 13.31
+	Rn
		92844 ITSN1_RAT (1-1665): 0: 771: 56.56		E9PSY8_RAT (9-312): 6.07e-16: 84.7: 15.41
+	Hs
		1078872 ITSN1_HUMAN (1-1665): 0: 780: 56.87		REPS2_HUMAN (14-99): 3.33e-12: 72.3: 24.42
+	Hs
		506537 BCR_HUMAN (746-1668): 6.74e-67: 251: 12.83		EPS15_HUMAN (1-862): 3.59e-115: 374: 42.20
+	Hs
		1078876 PREX1_HUMAN (1139-1566): 9.29e-71: 265: 19.28		ITSN1_HUMAN (1-522): 2.39e-32: 138: 13.31
+	Rn
		222475 KALRN_RAT (114-1582): 3.78e-80: 297: 12.94		MRCKA_RAT (415-784): 1.14e-21: 103: 9.45
+	Ce
		105247 G5ECK4_CAEEL (833-1632): 1.42e-72: 270: 15.28		Q9BIF4_CAEEL (118-345): 6.44e-09: 61.6: 24.68
+	Ce
		1308360 Q9BIF4_CAEEL (91-736): 3.33e-25: 115: 15.84		Q9U2T9_CAEEL (119-652): 4.86e-35: 146: 17.92